Reactome_cyp2e1_reactions

Author: ukbm

August undefined, 2024

WebNov 8, 2013 · CYP2E1 contributes to ROS generation in breast cancer cells. It has been shown that CYP2E1 is one of the most active CYP450 isoforms in generating intracellular … WebJun 1, 2003 · CYP2E1 LOCATION 10q26.3 LOCUSID 1571 ALIAS CPE1,CYP2E,P450-J,P450C2E Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool Other Information Locus ID: NCBI: 1571MIM: 124040HGNC: 2631Ensembl: ENSG00000130649 Variants:

UniProt

WebMay 9, 2024 · The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these … WebCYP2E1 reactions. CYP2E1 can metabolize and activate a large number of solvents and industrial monomers as well as drugs. This quality of CYP2E1 may make it an important … five thirty or five-thirty

levinelab.princeton.edu

WebJan 22, 2024 · CYP2E1 plays a suppressive role in hepatocellular carcinoma by regulating Wnt/Dvl2/beta-catenin signaling. Potential pathogenetic link between … http://www.reactome.org/content/detail/R-HSA-211999 WebHuman cytochrome P450 2E1 (CYP2E1) catalyzes the metabolism of numerous xenobiotics, including acetaminophen and ethanol. CYP2E1 expression is known to be extensively … can i wear jeans to a broadway show

CYP2E1 (cytochrome P450 family 2 subfamily E member 1)

WebCYP2E1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. WebJan 17, 2024 · Reactions specific to the hybrid N-glycan synthesis pathway. This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped … can i wear jeans for smart casualWebJul 25, 2013 · In 18206980, metabolizes AA Celecoxib metabolism AAP Gold Standard CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 cytochrome P450, family 2, subfamily E, polypeptide 1 P05181 1571 1.14.14.1 Human 9606 arachidonic acid metabolism KEGG: hsa00590 E 18206980 Can metabolize AA but had higher rates for … five thirty seven polls

"Webcyp2e1_reactions reactome_cyp2e1_reactions abacavir_transport_and_metabolism reactome_abacavir_transport_and_metabolism mastl_facilitates_mitotic_progression reactome_mastl_facilitates_mitotic_progression dna_damage_telomere_stress_induced_senescence … " - Reactome_cyp2e1_reactions

Reactome_cyp2e1_reactions

WebJul 30, 2024 · CYP2E1 is one of the fifty-seven cytochrome P450 genes in the human genome and is highly conserved. CYP2E1 is a unique P450 enzyme because its heme iron … WebJun 1, 2003 · REACTOME: R-HSA-1430728: Biological oxidations: REACTOME: R-HSA-211859: Phase 1 - Functionalization of compounds: REACTOME: R-HSA-211945: …

Did you know?

WebSep 2, 2024 · Drug–drug interactions (DDIs) have been recognized as a major cause of adverse drug reactions (ADRs) that leads to rising healthcare costs 1. Antagonistic drug–drug interactions may occur when a... WebCYP2E1 reactions. This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping …

WebMar 1, 2024 · Main methods: We conducted a panoramic analysis of CESC mutations based on The Cancer Genome Atlas-Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA-CESC) database. We made... WebNov 14, 2024 · Reactome functions both as an archive of biological processes and as a tool for discovering unexpected functional relationships in data such as gene expression profiles or somatic mutation catalogues from tumor cells.

WebSep 2, 2024 · The unravelled mechanisms could provide biological insights into potential adverse drug reactions of co-prescribed drugs. ... From Reactome 37, ... Xenobiotics (R … Webreactome_cyp2e1_reactions reactome_cytochrome_c_mediated_apop totic_response reactome_cytochrome_p450_arranged_b y_substrate_type reactome_cytokine_signaling_in_immu ne_system reactome_cytoprotection_by_hmox1 reactome_cytosolic_iron_sulfur_clus ter_assembly

WebAug 6, 2024 · REACTOME is an open-source, open access, manually curated and peer-reviewed pathway database. Our goal is to provide intuitive bioinformatics tools for the visualization, interpretation and analysis of pathway knowledge to support basic and clinical research, genome analysis, modeling, systems biology and education.

WebReactions The basic unit of Reactome is a reaction, which is defined as any molecular event; including binding, phosphorylation, biochemical catalysis, molecular transport and spontaneous molecular events. These reactions can involve any biological molecule, but are typically proteins and small molecules (chemical compounds). five thirty pmWebMar 21, 2024 · Entrez Gene Summary for CYP2F1 Gene This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. five thirty world cupWebREACTOME_CYP2E1_REACTIONS Human Gene Set: REACTOME_CYP2E1_REACTIONS For the Mouse gene set with the same name, see REACTOME_CYP2E1_REACTIONS See MSigDB license terms here. Please note that certain gene sets have special access terms. five thoughtsWebJul 30, 2024 · CYP2E1 is one of the fifty-seven cytochrome P450 genes in the human genome and is highly conserved. CYP2E1 is a unique P450 enzyme because its heme iron is constitutively in the high spin state, allowing direct reduction of, e.g., dioxygen, causing the formation of a variety of reactive oxygen species and reduction of xenobiotics to toxic … fivethiryeight best editing oscarWebResponsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases … five thousand and eightWebThe cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well … five thousand 2500 600 minutesWebFunction. A cytochrome P450 monooxygenase involved in the metabolism of fatty acids ( PubMed: 10553002, PubMed: 18577768 ). Mechanistically, uses molecular oxygen … five thirty on wedding invitation