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Klf9 function

WebSince Klf9 expression occurs predominantly in the pre-receptive stroma, this suggests a role for KLF9 in stromal-epithelial cross-talk important for endometrial receptivity. ... KLF9's function as a molecular brake for BMP2 could be manipulated to advance uterine receptivity in clinical conditions where delayed endometrial maturation may lead ... WebMar 11, 2024 · compromise anti-tumor immune function. We discovered that inhibition of Carm1, an epigenetic ... In turn, KLF9 induces expression of two regulators of ER calcium storage, TMEM38B and ITPR1 ...

JCI - Taking KLF9 to “Cort” for crimes against metabolism

WebApr 29, 2024 · KLF9, KLF10, and KLF14 increase transcription of Pgc1a, while KLF15 serves as a cofactor to increase transcription of the rate-limiting enzyme Pepck. Conversely, … WebJan 4, 2024 · Here, we show in mice that the TF Kruppel-like factor 9 ( Klf9) is elevated in quiescent RGLs and inducible, deletion of Klf9 promotes RGL activation state. Clonal analysis and longitudinal intravital two-photon imaging directly demonstrate that Klf9 functions as a brake on RGL symmetric self-renewal. tgr leash https://newlakestechnologies.com

miR-483-3p, Mediated by KLF9, Functions as Tumor …

WebJul 10, 2024 · Klf9 is a key feedforward regulator of the transcriptomic response to glucocorticoid receptor activity Ian Gans, Ellen I. Hartig, Shusen Zhu, Andrea R. Tilden, Lucie N. Hutchins, Nathaniel J.... We would like to show you a description here but the site won’t allow us. WebMar 21, 2024 · Complete information for KLF9-DT gene (RNA Gene), KLF9 Divergent Transcript, including: function, proteins, disorders, pathways, orthologs, and expression. … WebAug 23, 2024 · In the vascular system, KLF activities are regulated at both transcriptional and posttranscriptional levels. Growing in vitro, in vivo, and genetic epidemiology studies suggest that specific KLFs play important roles in vascular wall biology, which further affect vascular diseases. tgr jolly ramp

(PDF) ODP556 Krüppel-like factor 9 (KLF9) Links Hormone

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Klf9 function

KLF9 inhibits the proliferation, invasion, and migration of …

http://www.socolar.com/Article/Index?aid=100059662069&jid=100000004887 WebNov 1, 2024 · In turn, forced expression of KLF9 altered the baseline and GC/E2-responsive expression of several clock genes, indicating that KLF9 may function as a regulator of the core clock machinery.

Klf9 function

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WebFeb 5, 2024 · Krüppel-like factor 9 (KLF9), an axon growth-suppressing transcription factor, plays a key role in neuronal maturation and promotes oxidative stress. This study was … WebValidation of the Prognostic Value and Immune Function of KFL9 in KIRC. To further clarify the prognostic value of KLF9 in tumor tissues, we used univariate and multivariate Cox regression analyses to further demonstrate that KLF9 could be an independent prognostic factor in KIRC patients.

WebNov 16, 2024 · KLF9 acts as a critical mediator between the thyroid axis and hematopoiesis. Visual Abstract View large Download slide Abstract Congenital hypothyroidism (CH) is one of the most prevalent endocrine diseases, for which the underlying mechanisms remain unknown; it is often accompanied by anemia and immunodeficiency in patients. WebApr 13, 2024 · We have identified genomic targets of Klf9 in hippocampal neurons and created a foundation for future studies on how it functions in chromatin, and regulates …

WebAltered Krüppel-like factor 9 (KLF9) expression can regulate the progression of several cancers, including renal cell carcinoma (RCC). This study was conducted to investigate the role of KLF9 in the proliferation, invasion, and migration of RCC cells via regulation of stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor 4 (CXCR4). WebFeb 1, 2024 · Krüppel-like factor 9 (Klf9) is a ubiquitously expressed transcription factor that is a feedforward regulator of multiple stress-responsive and endocrine signaling pathways. We previously described how loss of Klf9 function affects the transcriptome of zebrafish larvae sampled at a single time point 5 days post-fertilization (dpf).

WebFeb 23, 2024 · Krüppel-like factor 9 (KLF9) links hormone dysregulation and circadian disruption to breast cancer pathogenesis Taken together, our findings support that …

WebApr 13, 2024 · The GSEA function in the clusterProfiler package was used to enrich the GSE38713 expression profile with "c2.cp.kegg.v7.4.symbols.gmt" and "c5.go.bp.v7.4.symbols.gmt" as reference gene sets 30 ... t grizzly no effort lyricsWebNov 21, 2014 · Kruppel-like factor-9 (KLF9), a member of the large KLF transcription factor family, has emerged as a regulator of oncogenesis, cell differentiation, and neural development; however, the molecular basis for the diverse contextual functions of KLF9 remains unclear. This study focused on the functions of KLF9 in human glioblastoma … t grizzly streamWebKLF9 INFORMATION. Proteini. Full gene name according to HGNC. Kruppel like factor 9. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. KLF9 (BTEB1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). tgr learning centerWebJun 18, 2012 · Klf9 Is a Cortisol-Dependent Marker for Epidermal Differentiation. Among the clock-controlled genes in epidermis a large subset of transcription factors was found that … tgr logisticsWebFeb 16, 2024 · Meanwhile, the luciferase assay showed that Krüppel-like transcription factor 9 (KLF9) was the downstream target of miR-93-5p. Forced expression of KLF9 blocked the function of miR-93-5p on H/R-treated HK-2 cells. Knockdown of circHIPK3 improved the renal function and reduced the apoptosis level in vivo. In conclusion, circHIPK3 … t grizzly satish lyricsWebJan 1, 2024 · KLF9 influences the expression of uterine epithelial genes through mechanisms likely involving its transcriptional activator and repressor functions and … symbolism of a batWebAltered Krüppel-like factor 9 (KLF9) expression can regulate the progression of several cancers, including renal cell carcinoma (RCC). This study was conducted to investigate … symbolism of a bee